Rapper/Bubblegum Pop Duets make cents

Apparently Chelsea Handler and Rapper 50 Cent may be dating .  Chelsea is quite the comedienne, television host, etc.  Although I do not see "singer" in her vita, I can't help wondering if this will be the next Bubble Gum Pop/Rapper duet to hit the airwaves.

What other she sings/he raps duets are we familiar with?  Katy Perry and Snoop Dogg sing "California Gurls", Rihanna and Eminem sing "Love the Way You Lie", Hayley Williams and B.O.B. sing "Airplanes", I would like to keep going, but being a hard core metalhead, I've run clear out of my knowledge base on this. 

Of course these femme singer/homme rapper duets are not new, Paula Abdul and MC Skat Kat introduced this phenomenon to us with "Opposites Attract" in 1989.  (By femme, of course I cleverly mean "female" in the French sense, not in the current slang sense of someone who is demonstrating exagerrated feminine traits, or in the LGBT sense as in the opposite of "butch".) 

Whether Bubblegum, or wailing, butch or femme, rap or hip-hop, one cannot deny that these current musical pairings are worth some cents...Airplanes has gone triple platinum, so has Love the Way You Lie (at least in Australia), and California Gurls double platinum (at least in Australia). 

Will Chelsea Handler and 50 Cent go all the way?  Maybe 50 Cent will help Chelsea find her voice and the two will duet their way to triple platinum in the charts of love.  Clearly, it only makes cents...